COX-1 and COX-2 are “iso-enzymes”, which have roles in the day-to-day life of pigs. Where COX-1 mainly has supportive features, COX-2 occurs when cells are damaged, leading to, for example, fever or pain. Non-steroidal anti-inflammatory drugs (NSAIDs) can suppress these iso-enzymes. Obviously, the trick is to get them to mainly tackle COX-2.